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The administration of Betamethasone is associated with an increase in blood sugar levels. This corticosteroid is used to reduce inflammation and suppress the immune response, and one of its metabolic effects includes the stimulation of gluconeogenesis in the liver, which can lead to higher blood glucose levels.

Patients receiving Betamethasone may experience hyperglycemia, especially those who are diabetic or at risk for diabetes, as corticosteroids can interfere with insulin action. It's important for healthcare providers to monitor blood glucose levels in patients on corticosteroids, especially during higher doses or extended treatment periods.

Understanding this response is crucial for managing potential side effects and ensuring that proper protocols are followed in monitoring and adjusting medications as needed.