What are common side effects associated with Calcium Channel Blockers?

Calcium Channel Blockers (CCBs) are a class of medications primarily used to treat hypertension and certain cardiac conditions. They work by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to muscle relaxation and vasodilation.

Among the side effects observed with CCBs, headache and hypotension are particularly relevant. Headaches can occur due to vasodilation and subsequent changes in blood flow dynamics, resulting in increased intracranial pressure. Hypotension, or low blood pressure, is a direct consequence of the vasodilatory effects of CCBs, which expand blood vessels and reduce vascular resistance, leading to a decrease in blood pressure levels.

The presence of both headache and hypotension aligns well with the pharmacological profile of calcium channel blockers, highlighting these side effects as common and significant in clinical practice. The other options, while they may represent side effects typically associated with various medications or health conditions, do not specifically capture the hallmark side effects seen with CCBs as accurately as the correct answer does.