Which condition is characterized by oversecretion of the adrenal cortex?

Cushing's Syndrome is characterized by an oversecretion of cortisol due to excessive production from the adrenal cortex. This condition can arise from various causes, including adrenal tumors, pituitary tumors that stimulate adrenal hormone production (also referred to as Cushing's disease), or ectopic ACTH production from tumors outside the pituitary gland. The excess cortisol leads to a variety of clinical manifestations such as obesity, unusual fat distribution, skin changes, and metabolic complications.

In contrast, Addison's Disease is associated with insufficient production of adrenal hormones, specifically cortisol and aldosterone. This condition results from damage to the adrenal glands, leading to symptoms like fatigue, weight loss, and low blood pressure.

Hypopituitarism refers to a reduction in the secretion of one or more of the pituitary hormones, which can impact adrenal hormone levels but does not directly involve oversecretion from the adrenal cortex.

Thyroid Storm is a severe and acute exacerbation of hyperthyroidism, unrelated to adrenal cortex function. It presents with hypermetabolism and significant systemic effects but does not involve cortisol levels or adrenal hormone secretion directly.

Thus, the description of oversecretion of adrenal cortex hormones aligns specifically with Cushing's Syndrome, making it the correct choice.