Which symptom is commonly associated with Cushing's Syndrome?

Cushing's Syndrome is characterized by an excess of cortisol in the body, which can lead to several distinct physical symptoms. One of the hallmark features of this condition is the presence of a buffalo hump, which is a term used to describe the accumulation of fat between the shoulders, giving a rounded appearance to the upper back. This symptom results from the body redistributing fat due to hormonal imbalances associated with excessive cortisol levels.

In contrast, weight loss is generally not associated with Cushing's Syndrome; instead, individuals often experience weight gain. While increased appetite can occur, it is typically the result of metabolic changes rather than a distinguishing feature of the condition. Additionally, low blood sugar is not common in Cushing's Syndrome, as the condition often leads to increased glucose levels due to the effects of cortisol on metabolism and insulin resistance. Thus, the presence of a buffalo hump is a clear and recognizable symptom that aligns well with the clinical picture of Cushing's Syndrome.